Wi Immunologists

Selected Wi publications

Pedersen, A.B. & Babayan, S. (2011). Wild immunology. Molecular Ecology doi: 10.1111/j.1365-294X.2010.04938.x
Babayan, S. A., Read, A. F., Lawrence, R. A., Bain, O. & J.E. Allen (2010) Filarial parasites develop faster and reproduce earlier in response to host immune effectors which determine filarial life expectancy. PloS Biology 8: e1000525
Little, TJ. Shuker, D.M., Colegrave, N., Day, T., and A.L. Graham. 2010. The coevolution of virulence: tolerance in perspective. PLoS Pathogens 6: e1001006
Auld, S.K.J.R., Scholefeld, J.A. and T.J. Little. 2010. Genetic variation in the cellular response of Daphnia magna (Cladocera: Crustacea) to its bacterial parasite. Proceedings of the Royal Society B DOI:10.1098/rspb.2010.0772
J. C. Coltherd, S. Babayan, L. Bunger, I. Kyriazakis, J. E. Allen and J. G. M. Houdijk (2009) Immune responses to macroparasites are sensitive to the interaction between genetic growth potential and protein nutrition in mice. Proceedings of the Nutrition Society (2009), 68 (OCE), E101
Vale, P and T.J. Little. 2009. Measuring parasite fitness under thermal variation. Heredity 103: 102-109
Smith, K.F., Acevedo-Whitehouse, K., & Pedersen, A.B. 2009. The role of infectious diseases in contemporary and future wildlife extinctions. Animal Conservation 12; 1-12
Lazarro, BP, Little TJ (2009) Immunity in a variable world. Philosophical Transactions of the Royal Society 364: 15-26
Afrane, Y.A., Little, T.J., Lawson, B.W., Githeko, A.K. and G Yan (2008) Deforestation and Vectorial Capacity of Anopheles gambiae Giles Mosquitoes in Malaria Transmission, Kenya. Emerging Infectious Diseases 14: DOI: 10.3201/ eid1410.070781
Davies, T. J. & Pedersen, A. B. [2008]. Phylogeny and geography predict pathogen community similarity in wild primates and humans. Proceedings of the Royal Society of London B: Biological Sciences 275 1695-1701.
Gráinne H. Long, Brian H. K. Chan, Judith E. Allen, Andrew F. Read and Andrea L. Graham. 2008. Experimental manipulation of immune-mediated disease and its fitness costs for rodent malaria parasites. BMC Evolutionary Biology. 8: 128
Gráinne H. Long, Brian H. K. Chan, Judith E. Allen, Andrew F. Read and Andrea L. Graham. 2008. Blockade of TNF-receptor 1 reduces disease severity but increases parasite transmission during Plasmodium chabaudi infection. International Journal of Parasitology. 38: 1073-1081
A. Fenton, T. J. Lamb & A. L. Graham. 2008. Optimality analysis of Th1/Th2 immune responses during microparasite-macroparasite co-infection, with epidemiological feedbacks. Parasitology 135: 841-53.
Pedersen, A.B. and Grieves, T. 2008. The interaction of parasites and resources cause crashes in wild mouse population. Journal of Animal Ecology 77, 370-377
Obbard, D.J., Callister, D.M., Jiggins, F.M., Soares, D., Yan, G and T. J. Little (2008) The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae. BMC Evolutionary Biology 8:274
Vale, PF, Stjernman, M, Little, TJ (2008). Temperature dependent costs of parasitism and the maintenance of polymorphism under genotype by environment interactions. Journal of Evolutionary Biology. doi:10.1111/j.1420-9101.2008.01555.x
A. L. Graham, I. M. Cattadori, J. Lloyd-Smith, M. Ferrari & O. Bjørnstad. 2007. Transmission consequences of co-infection: cytokines writ large? Trends in Parasitology 23: 284-91.
de Roode, J.C., Pedersen, A.B., Hunter, M. & Altizer, S. 2007. Host ecology affects virulence in a natural butterfly parasite. Journal of Animal Ecology 77, 120-126
Pedersen, A.B. & Fenton, A. 2007. Emphasizing the ecology in parasite community ecology. Trends in Ecology and Evolution 22:133-139
P’ng Loke, Iain Gallagher, Meera G. Nair, Xingxing Zang, Frank Brombacher, Markus Mohrs, James P. Allison and Judith E. Allen. 2007. Alternative Activation is an Innate Response to Injury that Requires CD4+ T-cells to be Sustained During Chronic Infection. Journal of Immunology. 179:3926-36.
Pedersen, A.B., Jones, K.E., Nunn, C.L. and Altizer, S.A. 2007. Infectious diseases and extinction risk in wild mammals. Conservation Biology 21: 1269-1279
Little, TJ and Killick, SC (2007). Evidence for a cost of immunity when the crustacean Daphnia magna is exposed to the bacterial pathogen Pasteuria ramosa. Journal of Animal Ecology (2007) 76, 1202-1207. doi: 10.1111/j.1365-2656.2007.01290.x
Duncan, A.B. and Tom J. Little (2007) Parasite-driven genetic change in a natural population of Daphnia. Evolution 61 (4), 796–803. doi:10.1111/j.1558-5646.2007.00072.x
Wedekind C, Walker M, Little TJ. 2006. The separate and combined effects of MHC genotype, parasite clone, and host gender on the course of malaria in mice. BMC Genet. 2006 Nov 21;7(1):55
Jensen, K.N., Little, T.J., Skorping, A., and D. Ebert. 2006. Empirical support for an optimal virulence in a castrating parasite. PloS Biology 4 e197 DOI: 10.1371
Andrea L. Graham, TJ. Lamb, Andrew F. Read, and Judith E Allen. 2005 Malaria-filaria co-infection in mice leads to increases in malarial parasitemia and virulence unless filarial infection achieves patency. Journal of Infectious Disease. 191:410-421
Little, T.J., Hultmark, D. and A.F. Read. 2005. Invertebrate immunity and the limits of mechanistic immunology. Nature Immunology 6: 651-654.
Graham, A. L., J. E. Allen, and A. F. Read. 2005. Evolutionary causes and consequences of immunopathology. Annual Review of Ecology, Evolution, and Systematics. vol 36: 373-398
Andrea L Graham, Matthew D Taylor, Laetitia Le Goff, Tracey J Lamb, Marisa Magennis and Judith E Allen. 2005. Quantitative appraisal of murine filariasis reveals greater susceptibility to Litomosoides sigmodontis among female hosts across all parasite life cycle stages. Microbes and Infection. 7: 612-618
A. L. Graham, J. E. Allen & A. F. Read. 2005. Evolutionary causes and consequences of immunopathology. Annual Review of Ecology, Evolution, & Systematics 36: 373-97.
Rick M Maizels, Adam Balic, Natalia Gomez-Escobar, Meera Nair, Matt D. Taylor and Judith E Allen. 2004. Helminth Parasites: Masters of Regulation. Immunological Reviews. 201: 89-116
Mitchell, S.E., Rogers, E., Little, T.J. and A.F. Read. 2005. Host-parasite and genotype by environment interactions: Temperature modifies the potential for selection by a sterilising pathogen. Evolution 59:70-80
Fenton, A. and Pedersen, A.B. 2005. Community epidemiology in theory and practice: A conceptual framework for describing transmission dynamics in multiple hosts. Emerging Infectious Disease11:1815-1821
A. L. Graham. 2003. Effects of snail size and age upon the prevalence and intensity of avian schistosome infection: Relating lab to field studies. J Parasitol 89: 458-63
Little, T.J., O'Connor, B., Colegrave, N., Watt, K. and A.F. Read. 2003. Maternal transfer of strain-specific immunity in an invertebrate. Current Biology 13: 489-492.
Carius, H-J, Little, T.J., and D. Ebert. 2001. The potential for frequency-dependent selection and coevolution in a Daphnia-microparasite system. Evolution 55: 1136-1145
Little, T.J. and D. Ebert. 2000. The cause of parasitic infection in natural populations of Daphnia (Crustacea: Cladocera): the role of host genetics. Proceedings of the Royal Society of London B 267:2037-2042.
Judith E. Allen and Rick M. Maizels. 1997. Th1/Th2 - Reliable Paradigm or Dangerous Dogma? Immunology Today. 18:387-392.

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